1.
Comparative Efficacy Of Buparvaquone And Oxytetracycline Against Theileriosis In Cattle And Their Effect On Blood
by Sarvat Yab Khan | Prof.Dr.Muhammad Ashraf | Dr.Haji Ahmad | Dr.Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1998Dissertation note: Theileriosis is a serious disease of the cattle which is caused by species of Theileria resulting in death due to severe anaemia. The present study was conducted to evaluate the comparative efficacy of buparvaquone (Butalex, ICI) and oxytetracycline (Terramycin 100 PVP) and their effect on various blood parameters, viz, total erythrocytic count (TEC), total leukocytic count (TLC), packed cell volume (PCV) and haemoglobin estimation (Hb) in and around Lahore.
Thirty infected cattle showing clinical signs of Theileriosis (diagnosed based on blood smear examination) were used in this study. These animals were randomly divided into 3 groups designated as A, B and C comprising 10 animals each. Besides this 10 healthy cattle were kept as control as group D.
Haernatological examination revealed a significant decrease in the erythrocyte count, packed cell volume and haemoglobin level of the infected cattles. Total leukocyte count was also decreased. Animal of group A was treated with single intramuscular injection of Butalex at the dose rate of 2.5 mg/kg body weight. The efficacy of the drug was 90 per cent. There was marked increased in the erythrocyte, leukocyte, packed cell volume and haemoglobin concentration.
Group B was treated with intramuscular injection of Terramycin 100 PVP at the dose rate of 10 mg/kg body weight. The efficacy of the drug was 40% and there was slight increase in the haematological values. riThe haematological values of group C were much more decreased while in group D, these values were just same.
From this study, it is concluded that buparvaquone 2.5 mg/kg body weight (Butalex ICI) is the drug of choice for the treatment of Theileriosis under field condition in our country.
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2.
Prevalence Of Ascaridiosis In Domestic Pigeons, Its Chemotherapy And Effect On Blood Parameters In Lahore
by Imran Ali | Dr.Muhammad Sarwar Khan | Dr.Haji Ahmad | Dr.Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1998Dissertation note: This project was designed to study the prevalence of Ascaridia çolumbae in domestic pigeons and its chemotherapy with two anthelmintics to see the efficacy of two drugs and effect on some blood parameters (TLC and DLC).
To find out the prevalence, fifty pigeon shops and houses of pigeon owners were visited in and around Lahore each month. A total of 150 samples from June to August 1998 were collected. An overall prevalence recorded in domestic pigeons was 60 percent. It was highest (72%) in August and lowest (58%) in July. The prevalence of infection was higher in birds raised under unhygienic and poor managemental conditions.
For drug efficacy and haematology, 60 pigeons were purchased from local market and divided into 4 groups comprising of 15 birds each and grouped as under:
Group A (15 birds) infected and medicated with Albenzole.
Group B (15 birds infected and medicated with Chanazole.
Group C (15 birds) infected and non-medicated (control)
Group D (15 birds) Non-infected and non-medicated (control).
Three samples of faeces and blood were collected from each group on zero day, 7th day, 12th day of medication. In group A, egg count decreased to 60.8% and 96.70% on 7th and 12th day of medication respectively. In group B, egg count decreased to 68.60% 86.0% on 7th and 12th day respectively. While in group C, egg count increased to 7.70% and 218% on 7th and 12th day of medication. Group D, remained free from infection and non-medicated throughout the experiment and kept as control. As regards the efficacy of drugs, the Albenzole was found highly effective and reduction percentage was 96.70 eggs ocr gram of faeces. While in Chanazole reduction percentage was 86.0. Total leukocyte count in group A, B and C increased on zero day, 7th day and 12th day of medication. In group 0, total leukocyte count remained constant throughout the experimental period.
Availability: Items available for loan: UVAS Library [Call number: 0569,T] (1).
3.
Prevalence And Chemotherapy Of Strongylosis And Its Effect On Various Blood Parameters In Horses
by Abid Saleem | Dr.Khalid Pervez | Dr.Haji Ahmad | Dr.Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1998Dissertation note: The present project was designed to find out the prevalence of strongylosis, to test the anthelmintic efficacy of Albendazole, Oxfendazole and Piperazine and to study the effect of strongyloids on blood parameters.
For this purpose the faecal samples of one hundred and twenty horses were processed through coprological examination. Out of 120 horses 68 were found positive, so the prevalence of strongylosis was recorded as 56.66%. Out of the positive animals, 60 were randomly divided into four groups A, B, C and D comprising of 15 animals in each group. Each animal of group A was given Farbenda (7.5 mg/kg body weight), group B was given Oxafax (10 mg/kg body weight), group C was given Coopane (0.2 g/kg body weight) while group D was kept as control (untreated). The efficacy of anthelmintics was evaluated on the reduction of eggs per gram (EPG) of faeces on 7th, 14th and 21st day post-medication. Efficacy of Farbenda (Albendazole) was 64.2%, 53.1% and 42.1% on 7th, 14th and 21st day, respectively. Efficacy of Oxafax (Oxfendazole) was 100%, 98.7% and 98.1% on 7th, 14th and 21st day, respectively. Efficacy of Coopane (Piperazine) was 52.3%, 38.8% and 28% on 7th, 14th and 21st day, respectively. It was concluded from above results that Oxfendazole was found the most effective than Albendazole and Piperazine, while Albendazole showed better efficacy than Piperazine.
Haematological parameters showed significant reduction in total erythrocyte count (TEC), haemoglobin (Hb) level and packed cell volume (PCV) while total leukocyte count (TLC) remained within normal limits.
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4.
Comp;Arative Efficacy Of Ivermectin, Levamisole And Levamisole Plus Cobalt Against Gastro Intestinal Nematodes Of Sheep Under Field Conditions In District Kohat
by Zahir Shah | Dr.Iftikhar Gul Ahmad | Dr.Haji Ahmad | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1999Dissertation note: The present project was designed to evaluate the anthelmintic efficacy and effect of treatment on weight gain of sheep. Fighty sheep of local breed aged 8-10 months positive for gastro-intestinal nematodes were selected from surrounding areas of district 1(ohat (N.W.F.P) and were divided into 4 groups (20 animals in each group). Group A, B and C were given Ivermectin (0.2mg/kg body s/c), Levarnisole 7.5 mg/kg body orally) and Levamisole plus Cobalt (7.5 mg/kg body weight orally) respectively and group U remained as untreated control group.
Egg per gram (EPG) of faeces were recorded on "0" day before treatment and on 7th, 14th, 21st and 28th days after treatment.. The efficacy of these drugs were evaluated on the basis of reduction of eggs per gram (EPG) of faeces after medication. These drugs showed a progressive decrease in the faecal egg counts. The percent efFicacy of Tvermectin, Levamisole and Levamisole plus Cobalt on 7th, day after medication was 100%, 98.65% and 98.73% respectively and on 14th, 21st and 28th days, the efficacy of all drugs was 100%. rIIIere was no significant difference (P<0.01) in effectiveness of the drugs.
However, there was highly significant difference (P<0.01 between treated and control groups.
The Weights of animals were recorded on "0" day before medication and on 7th, 14th, 21st and 28th days after medication. The average weight gain in group A, B and C was 1.8kg, 2.10kg and 3.21kg respectively and the percentage of increase in live weight was 6.57% in group A, 7.63% in group B and 12% in group C. Whereas members of control group reduced their weight by 1.68kg. There was highly significant difference (P<0.01) among the treatments as well as the control group.
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5.
Prevalence Of Gastro Intestinal Nematodes In Aquatic Birds At Lahore Zoo And Their Chemotherapy With Three Different Anthelmintics
by Ihsanullah | Dr.Iftikhar Gul ahmad | Dr.Haji Ahmad | Dr.Muhamad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1999Dissertation note: The present study was undertaken to find out the prevalence of gastro-intestinal nematodes in aquatic birds at Lahore zoo and to evaluate the comparative efficacy of Albendazole (Albenzole granules; Selmore Agencies), Levamisole (Vormatox liquid; Welcome Pak. Ltd.) and piperazine (Coopane powder; Glaxo Weilcome). Ninety faecal samples were examined in Medicine Laboratory, College of Veterinary Sciences, Lahore with direct smear method or flotation technique for identification of nematode ova. Seventy one of 90 (78.89%) were found positive for single or mixed infections of Capillaria anatis (38.89%), Trichostrongylus tenuis (26.66%), Amidostornum anseris (21.11%), Tetrameres fissispina (14.45%), Heterakis gallinae (11.11%) and Ascaridia gaul (5.56%).
Out of seventy one infected birds, 60 were chosen randomly for medication and divided into three groups, each consisting of 20 birds (A = crane group, B = duck group and C = geese group). These three groups were further divided into four sub-groups (Al, A2, A3 and A4, similarly Bi, B2, B3, B4 and Cl, C2, C3 and C4), each comprising of 5 birds.
Faecal samples of the experimental birds were examined for counting of eggs per gram of faeces on day "0" (pre-medication) with McMaster technique (Soulsby, 1982).
Albendazole was given orally to sub-groups Al, Bi and Cl, similarly Levamisole and Piperazine were given to sub-groups A2, B2, C2 and A3, B3 and C3. The sub-groups A4, B4 and C4 were kept as untreated infected controls.
Faecal egg counts were again carried out on days 7 and 14 of medication and the results were compared with control sub-groups. Regarding the efficacy of anthelmintics, piperazine was highly effective with reduction of 88.66 and 99.31 per cent eggs per gram of faeces on 7th and 14th day of medication. Levamisole was found to reduce 84.38 and 97.57% eggs per gram of faeces followed by Albendazole with 83.16 and 95.79% reduction in the eggs per gram of faeces.
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6.
Prevalence Of Nematodes & Comparative Efficacy Of Albendazole, Mebendazole & Niclosamide Against Nematodes, In Wild Felidae
by Waqar Ali Khan | Dr.Khalid Pervez | Dr.Haji Ahmad | Dr.Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1996Dissertation note: The present study was conducted to estimate the efficacy of Bovisol (Albendazole), Vermox (Mebendazole) and Yomesan (Niclosamide) against nematodes i.e. Toxocara canis, Toxocara mystax and Ancylosloma braziliense in wild felidae, kept in captivity in Lahore Zoo and Lucky Irani Circus, because wild felidae are prone to a number of parasitic infection and zoological gardens served as permanent source of parasitic infestation.
A survey was carried out to estimate the prevalence of Toxocara canis, Toxocara mystax and Ancvlostoma braziliense in wild felidae kept in Lahore Zoo and Lucky Irani Circus. The incidence rate of these parasites was 84.62%, 84.62% and 69.23%, respectively in the Lucky Irani Circus; and 62.07%, 48.28% and 20.69%, respectively in the Lahore Zoo. All the animals showing infection were selected for therapeutic trials.
The anthelmintic trials were conducted on 19 and 13 wild felidae kept in the Lahore Zoo and Lucky Irani Circus, respectively. In each experimental Station, i.e. the Lahore Zoo and Lucky Irani Circus, four groups designated A, B, C and D were made. Groups A, B and C were treated with Bovisol (Albendazole), Vermox (Mebendazole) and Yomesan (Niclosamide), respectively. While one group i.e. D, was kept as control (untreated). The percent efficacy of each drug was determined on the basis of reduction in the number of ova discharged in the faeces of experimental animals on 7th, 14th, 21st and 28th day after medication.
Results showed that Vermox (Mebendazole) and Bovisol (Albendazole) are approximately equally effective against roundworms and hookworms. Efficacy of Yomesan (Niclosamide) did not show good results throughout the experiment. The efficacy of all the three anthelmintics lowered down with the passage of time.
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7.
Clinico Haematological And Therapeutic Studies On Experimentally Induced Spirochaetosis In Broilers
by Ashraf Qaisrani, M | Muhammad Sarwar Khan | Dr.Haji Ahmad | Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 2000Dissertation note: To final out the comparative efficacy of different control measures against Argas persicus, In-Vitro and In-Vivo studies were carried out for the in-Vitro studies three thousand soft ticks Argas Persicus at different stages of their development were used in the experiment. The ticks were divided in to 5 groups A, B, C, D and E having 600 ticks in each group. The ticks of each group (600) were further divided in to three replicates having 200 ticks in each. The ticks were maintained in small plastic boxes containing tick rearing medium at a controlled temperature of 25 Co and 60% relative humidity. The 5 treatments are applied with a small (1 liter) hand held sprayer at the rate of 20ml per box 345 cm2 surface area. The first application was made after 24 hours and repeated twice at 48 hours intervals. On day 0,3,5,7 and 10, the ticks were separated from the manure by immersing the manure in water and retrieved the ticks with the help of sieve. The ticks relating to each group were counted and the counts of each group were compared. The reduction in the counts in test groups as compared to control group A indicated the efficacy of the treatment. It was noticed by the comparative mortality of the ticks in the replicates of different groups that in mortality of ticks in Group A occurred as 6.17% in B as 67.67% in C as 70.67% , in D as 100% and in E as 71.83%. The findings of the In Vitro experiment showed that the efficacy of Tiekide was 100% and in ranking order was placed at No. 1 amongst the test groups and the difference was statistically significant (P<0.05) as compared to B, C and E groups. However the findings of Groups B, C and E were not significant amongst each other (P>0.05). For the In-Vivo studies, the experiment was conducted on a layer farm infested with Argus persicus. A total of 100 layers infested with Argas persicus were reared under experimental conditions on particular farm. One hundred infested birds were divided into 5 groups i.e A,B,C,D and E, each group consisting of 20 birds. The ticks of all members of the groups were counted on day 0,3,5,7 and 10. Group A acted as infested and non treated, B was treated by application of EM1 under the infested wings, C was applied EM5, D was applied Tiekide (Homoeopathic formula) under the wings the medicine was also orally administered @ 2 drops in 1 ml water and members of Group E were applied 1% solution of Ivomec (Ivermectin). The results indicated that the reduction in the mean tick counts was 95.74% in Group D which was placed at No. I, in descending order the mean tick counts reduced by 70.97% in Group E, 68.59% in Group C, 67.63% in Group B and only 1.93% in control Group A. The Tiekide was claimed to be a drug of choice.
Availability: Items available for loan: UVAS Library [Call number: 0641,T] (1).
